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November 16, 2009 5:52 PM PST

A new antidepressant really turns women on

by Elizabeth Armstrong Moore
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To all the men (and women) I've ever heard complain about the female libido, it's time to take the batteries out of your high-tech remote-control sex toys.

Flibanserin appears to be a highly effective libido booster in women who report low sexual desire, three new trials find.

(Credit: Simple Insomnia/Flickr)

Flibanserin, a drug originally designed to fight depression, turns out to be an ineffective antidepressant but a highly effective libido booster in women who report low sex drives, according to results pooled from three separate clinical trials. (It's long been thought that antidepressants suppress sex drives, so it makes its own strange sense that a poor antidepressant might not have the same suppressing effect.)

"It's essentially a Viagra-like drug for women in that diminished desire or libido is the most common feminine sexual problem, like erectile dysfunction is in men," reports John Thorp Jr., a principal investigator in the studies and the McAllister distinguished professor of obstetrics and gynecology at the University of North Carolina at Chapel Hill School of Medicine.

It's not terribly surprising that flibanserin was not originally designed to boost the female libido, since this is a notoriously complicated task compared to the notoriously uncomplicated approach in men of simply regulating blood flow. More surprising is that these are purported to be the first trials ever to test a female libido therapy in the brain; one would think that all the scoffing women do about men thinking with their "other" heads would indicate women's tendency to do that sort of thinking with the head that sits on their shoulders.

Hypoactive sexual desire disorder, a bulky arrangement of syllables that risks causing the very thing it names, affects anywhere from 9 percent to 26 percent of women in the U.S., studies show. But that doesn't mean you should throw away those high-tech sex toys and run to your local pharmacy; flibanserin is still an investigational drug, available only to those women who've agreed to participate in clinical trials.

The trial results were presented by principal investigator Elaine E. Jolly from the University of Ottawa in Canada on Monday at the Congress of the European Society for Sexual Medicine in Lyon, France.

All three trials were funded by Boehringer Ingelheim Pharmaceuticals, a manufacturer of flibanserin. That means until further studies are done without BIP funding, these results should be viewed with a level of skepticism; developing the first successful female libido booster could be a way for the company that designed such a poor antidepressant to save face.

That brings me to a final point: since women who do not suffer from hypoactive sexual desire disorder might be just the type to enjoy such things as sex toys and libido boosters recreationally (some women take Viagra for fun), one wonders what effect, if any, flibanserin will have on them.

Elizabeth Armstrong Moore is a freelance journalist based in Portland, Ore. She has contributed to Wired magazine, The Christian Science Monitor, and public radio. Her semi-obscure hobbies include unicycling, slacklining, hula-hooping, scuba diving, billiards, Sudoku, Magic the Gathering, and classical piano. She is a member of the CNET Blog Network and is not an employee of CNET.
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by papsc November 16, 2009 6:46 PM PST
Oh man!!! well at least they are finding something for us woman finally
Reply to this comment
by HappyApe November 16, 2009 6:58 PM PST
Would it be considered morally wrong to slip this into my girlfriend's drink/food?
Reply to this comment
by gerrrg November 16, 2009 9:35 PM PST
It's as I always say...If you have to ask, you already know the answer to your question.
by Seaspray0 November 17, 2009 9:52 AM PST
@gerrrg. I'm past the asking stage. Now I beg.
by gerrrg November 16, 2009 7:09 PM PST
I'm confused; why would a drug that drives your libido be seen as an ineffective anti-depressant? Seems like, if you've got the desire to have sex, and the act of having sex pumps your head full of endorphins, that would surely counter your depression, no?
Reply to this comment
by lordeagle November 16, 2009 10:41 PM PST
Because they dont want to write the following as how to use the drug:
1. Take a pill
2. Have sex
3. Repeat steps 1 and 2 as necessary.

;)
by FoggsKnackers November 16, 2009 7:20 PM PST
Viagra solves a bio-mechanical problem, it does not increase libido or sexual desire.
Reply to this comment
by atish505 November 17, 2009 1:10 AM PST
Mechanical problem as in 'drilling', lapping, honing .... LOL.
by luke_marsh November 17, 2009 1:58 AM PST
And heroin addiction was destroyed over night.
Reply to this comment
by henebry November 17, 2009 4:19 AM PST
Actually, Viagra was also originally intended to do something else: fight high blood pressure. Before Viagra, impotence wasn?t taken very seriously as a problem by drug manufacturers. It was the domain of quack science, and it wasn?t clear whether prescriptions would be paid for by insurance.
Reply to this comment
by tinlizziedl November 17, 2009 8:49 AM PST
I think it's a sad comment on our healthcare system that more insurance companies pay for Viagra and its brethren than for "the pill." Should this drug actually prove it's claims, do you think it will have a more difficult time getting insurances to pay for it than Pfizer did with its "get some lead in your pencil" drugs?
by krashcoarse November 17, 2009 5:56 AM PST
In seriousness, this could be a real godsend to struggling couples out there.
But really??: head researcher named "Jolly" ?? LOLZ!
I think they should nickname the stuff after her! "Take your pills and get your jollies"

HA!
Reply to this comment
by teraguru1 November 17, 2009 6:55 AM PST
What does this have to do with TECH? Shouldn't this be on MSN, is cnet turning into a GOSSIP site now.
Reply to this comment
by topanaris November 17, 2009 8:41 AM PST
Tech does not only exist in a cold server room my friend. Besides it does break the monotony of the ends M$ vs Mac flamewars that plague CNET Blogs.
by alegr November 17, 2009 11:15 AM PST
OK. Now it's my turn.
1. I'm sure the women who use Mac don't need this.
2. Those unfortunate men who futz with Windows all day long are too tired to ask anything from their girlfriends (if they even got them that is).
by tinlizziedl November 17, 2009 8:11 AM PST
While this is a good development for womens' health, I find I'm dreading the inevitable commercials. We are already inundated with all the commercials for drugs to "boost male performance."

Darwin must be spinning in his grave- Now the world has evolved to the point of procreation of the best drug user....
Reply to this comment
by Dalkorian November 17, 2009 12:07 PM PST
Idiocracy, here we come.
by papsc November 17, 2009 12:17 PM PST
Look here all you men, you beg and beg for it, and now they might have a drug that makes US beg for it and you want to complain? SHUT UP!
Reply to this comment
by pjk0 November 17, 2009 2:03 PM PST
First of all, you people apparently are trying to be The Register, but without the humor. Fail.

If I were you, I would stick to the on-topic news stories.

But since you brought it up: the pharmaceutical industry's latest "holy grail" has been some sort of "female viagra", because they salivate by the bucket at the potential profits. Problem is, the industry keeps trying to invent "problems" that don't exist.

Case in point: the A-number-1 reason that someone has a "low sex drive" is that they AREN'T TURNED ON. And one of the key reasons for that is that their presumed partner is a jerk. No amount of "female viagra" is going to magically turn your self-centered, misogynist jerk of a boyfriend into a beautiful person.

Next.
Reply to this comment
by Dr_Zinj November 18, 2009 4:47 AM PST
Most men are in a constant state of desire anyway, so a drug to increase their desire isn't likely to have much effect. The MECHANICS on the other hand, can be problematic. As they say, the spirit is willing but the flesh is weak. Hence, then myriad commercial spots for viagra, enzyte, and other ED treatment drugs.

I'm fairly certain the major reason for women having such a low sex drive is the sheer incompetence of most men/boys to do a good job for the girl/woman for her first time. All the worry, not much fun, not worth it.
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