It's our preference to use a text editor, like HomeSite, TextPad or TextMate, to "hand code" everything, rather than to use a wysiwyg (what you see is what you get) HTML and CSS authoring program, like Dreamweaver. We just find it yields better and faster results.
At my company we've been through this ordeal several times, finally settling in on PHP templates for the corporate site and Atlassian's Confluence for our developer sites. The corporate site still requires manual code intervention but we're modularized enough where the risk vs. reward is still OK. I'm waiting for Matt Asay to give me the green light on the Alfresco web product before we move to a full blown CMS. He knows that I am a difficult customer.
In the meantime I continue to enjoy/loathe our blog system here at CNET that requires us to format HTML. I like the control versus other blog tools, but it gets a little onerous.