CNET calls the Logitech Harmony One "arguably the best consumer remote control currently available," and I agree. I've owned one for about two years, and it's without a doubt my favorite remote ever.
Alas, Logitech still sells it for $250, same as when it debuted in early 2008. But right now, CompUSA is offering the Harmony One for $139.99 shipped.That's after applying coupon code OXG277 at checkout.
(If this deal sounds a bit familiar, that's because I posted a similar one back in October--but the price then was $150, and it was a refurb. This one's brand-new!)
The Harmony's claim to fame is a simple (relatively speaking) Web-based interface for setting up your devices, programming "activities" (aka macros), and so on.
This particular model features a color touch screen, a perfect button layout, and a docking station that keeps the rechargeable battery topped off.
CNET's review (and the above video) should tell you everything you need to know about the Harmony One. For what it's worth, CompUSA customers rated it 5 stars on average, while some 900 Amazon buyers rated it 4.5 stars. Needless to say, it's a winner.
Thus, if you're in the market for the ultimate universal remote, this is the best deal I've seen yet. (If you know of a better one, be sure to mention it in the comments!)