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April 3, 2008 4:00 AM PDT

Why Web 2.0 is an easier investment than biotech

by Jim Kerstetter

Just five years ago, the high-tech industry was in the dumps and fickle Silicon Valley hearts were turning to biotechnology and so-called convergence companies that would combine computing know-how with life sciences.

At the time, it seemed like the best place to move the investment chips: The ideas behind social media were just starting to coagulate. The telecommunications build-out of the 1990s had long since ended. And big tech-boom buyers like Yahoo (which my CNET News.com colleague Charlie Cooper to this day curses for forever saddling us with billionaire basketball maven Mark Cuban) had shut the money spigot.

Meanwhile, human genome research was opening new windows for start-ups. And the potential for harnessing for genetics research the high end but low-cost computing power demonstrated by Google's Linux-based data centers had entrepreneurs thinking big.

So why don't we hear very much about biotech, and so, so much about Internet companies? Well, it turns out biotech is a difficult business, and Web 2.0, by comparison, isn't. (News.com's Stefanie Olsen has a broader look at how VCs are girding for what could be a rough economy in the months ahead.)

A former colleague who covered the biotech boom of the early 1990s once explained to me why some venture capitalists steer clear of biotech and health care: In tech, you have product cycles that last two or three years, maximum. It doesn't take all that long to see if you're going to get a return on your money. (With Web 2.0 investments that cycle is probably even shorter.)

But in biotech and health care, product cycles last two or three decades because of everything from regulatory approval to testing. If you're a middle-aged investor, you're hoping you'll live long enough to see your money pay off. Some of the savviest investors in Silicon Valley, such as Elevation Partners' Roger McNamee, have traditionally steered clear of biotech for exactly that reason. Even for people accustomed to taking financial risks, biotech can be too risky.

That's not to say there's no money going into biotech and health care research. In fact (and here's where the analysis gets a little tricky), the life sciences category received more investment than any other category last year: $9.1 billion in 862 deals, according to Thomson Financial and the National Venture Capital Association. That was 31 percent of all venture capital invested and well up from $7.6 billion in 2006.

But these are long-term investments. Making money pay off in life sciences is still as hard as it ever was. In the first quarter of 2008, there were five venture-backed M&A deals in life sciences, according to NCVA. Three of them had a combined disclosed value (the other two weren't disclosed) worth a combined $229.3 million.

The real action was in information technology, where there were 41 deals in the first quarter, 15 of them disclosed for a total of $1.996 billion. Of those, 12 were Internet companies, 8 of them disclosed for a $1.678 billion total.

Life sciences did have a big advantage on the public markets. There were four life science initial public offerings (only one of those in biotech) in the first quarter that raised a combined $221 million. There was only one information technology IPO--ArcSight, a security management software and service company that raised $61.8 million.

So the bottom line is, well, the bottom line. Even with little appetite for tech IPOs, investing in a Web 2.0 provides a VC with an easier way to cash in than investing in biotech or health care. Are the rewards for a big hit not as great in Web 2.0 investments? Maybe so. But with increasing pressure from their investors to show how they're putting their funds to work, VCs are making the safer call.

Jim Kerstetter has been writing about the high-tech industry for more than 13 years, as a senior editor at PC Week, a Silicon Valley correspondent at BusinessWeek, and now an executive editor at CNET News. He moved back to Boston because he missed the Red Sox. E-mail Jim.
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Add a Comment (Log in or register)
To Sum it UP
by dascha1 April 3, 2008 5:16 AM PDT
So by your report what I'm hearing is that the biotech is too risky
an investment for long-term (or breakthrough in shorts).
Hmm... sounds a little like say the music business now...
Everybody wants to have that song that makes them heal, but
the majority consensus, including the journalists, is NEVER pay
those who develop it and distribute it?

It's grate isn't it?
Reply to this comment
by kabir125 October 13, 2008 5:21 AM PDT
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Here?s our market view on American stock market for 10th October, 2008

The stock market has collapsed - since Sept. 19 the DJIA is down 25% and the S&P 500 is down 28% and down 42% from a year ago.

How can this happen so quickly and so dramatically when so many good things have occurred? Oil is down to $82 a barrel; interest rates are very low; the dollar is up; valuation levels are extremely attractive among many blue chip stocks.

What's the real problem? The problem that is killing the stock market is a lack of hope about the future.

Hope springs from optimism that is based on facts and history. Look at the history of America and really all of mankind. Life is full of setbacks and problems - that's just the deal. But this too shall pass, as all scary periods have.

Doomsayers have been around forever and their batting average is zero. Buying stock is based on hope - hope for the future. If one doesn't have hope, they shouldn't be in this business.

So what is the best service we, as professionals, can provide for our clients?

First, discuss the fact that we are dealing with serious problems but it is not at all like 1929. The Federal Reserve and the Treasury Department are doing many things to restore confidence in the financial system. There is global coordination in attacking the problem, which is lack of confidence.

Tell your clients to look at history of our great nation and what has happened since 1776 when we faced very serious problems. The stock market actually rose steadily about six months after Pearl Harbor and until the end of WWII even though the outcome was not at all clear for several years.

No one knows when the stock market will bottom and a new bull will commence. We do know that stocks and mutual funds offer the best values we have seen since Black Monday, Oct. 19, 1987.

Almost all Americans have hope about the future of our nation, but they need help to control their normal fears.

ThePowerStocks.com Team
Get 56 days free trial on ThePowerStocks.com exclusive newsletter. Offer Limited.
http://www.thepowerstocks.com
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