epilepsy

Bots beat humans probing brain's neural activity

In what could be a major boon for the study of brain disorders such as schizophrenia, Parkinson's disease, autism, and epilepsy, researchers at MIT and Georgia Tech say they've figured out how to automate finding and recording information from neurons in live brains.

The process, described this week in the journal Nature Methods, involves a robotic arm guided by a cell-detecting algorithm that can identify and record data from neurons faster and more accurately than we mortal humans.

"In all [the abovementioned disorders], a molecular description of a cell that is integrated with [its] electrical and circuit … Read more

New mini sensor can measure brain's magnetic activity

An atom-based magnetic sensor the size of a sugar cube has successfully measured human brain activity, a milestone that could ultimately lead to advancing our understanding of a wide range of neurological conditions and diseases, according to researchers at the National Institute of Standards and Technology (NIST).

We first reported on an earlier iteration of the sensor, which has been in development since 2004, back when the team was first able to use the sensor to track a human heartbeat in 2010.

This week, the researchers report in the journal Biomedical Optics Express that their tiny sensor -- which consists … Read more

Early-warning software could reduce false alarms of seizures

Of the 50 million people worldwide estimated to have epilepsy, almost a third do not respond to treatment. Those patients must rely on implantable anti-seizure devices that detect pre-seizure electrical activity and shoot small electrical impulses to the brain to interrupt the seizures.

The downside is that the tech, still early in development, also produces false positives, causing devices to send currents to the brain when a seizure is not actually occurring. One new approach, developed by a biomedical and electrical engineer at Johns Hopkins University, appears to reduce those false alarms.

Tested on real-time recordings of brain activity in … Read more

Ultrathin silk-based electrodes as brain implants

Silk is not only flexible, it is also transparent and strong, and the rate at which it dissolves can be manipulated. So researchers at the University of Illinois, Urbana; Tufts in Boston; and the University of Pennsylvania decided to build silk-based brain implants, using electrode arrays with silk proteins and thin metal electrodes.

Since silk is biocompatible and water-soluble, it dissolved in the brains of the cats they studied, leaving the mesh-like electrodes, which are about 1/40 the thickness of a standard sheet of paper, literally hugging the brains' contours.

The cats were anesthetized, but their eyes still functioned, … Read more