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cornea

Playing molecular Legos with viruses

It may be benign, but researchers have turned the virus M13 into a sophisticated engineering tool that could lead to the manufacturing of materials with biomedical properties that can be fine-tuned, such as bone, skin, and corneas.

"We took our inspiration from nature," said Seung-Wuk Lee, an associate professor of bioengineering at UC Berkeley who describes the team's self-templating material assembly process in the journal Nature. "Nature has a unique ability to create functional materials from very basic building blocks. We found a way to mimic [this]."

Lee points to the protein collagen as the … Read more

Biosynthetic corneas help restore light--and sight

In development for more than a decade, biosynthetic corneas implanted in 10 Swedish patients over a two-year clinical trial are helping most of those patients see again, according to researchers in Canada and Sweden.

"This study is important because it is the first to show that an artificially fabricated cornea can integrate with the human eye and stimulate regeneration," senior author May Griffith of the Ottawa Hospital Research Institute said. "With further research, this approach could help restore sight to millions of people who are waiting for a donated human cornea for transplantation."

Griffith and colleagues … Read more