clinical

Benjamin Franklin once advised a friend to take older women to bed because, figuratively speaking, "in the dark all cats are gray." Well, not these kittehs.

Researchers in the U.S. and Japan have developed green-glowing kittens with resistance to the feline version of AIDS, which may help work on AIDS research in humans.

In a study published in Nature Methods, researchers from the Mayo Clinic and Yamaguchi University took a genome approach to producing cats that are apparently resistant to feline immunodeficiency virus (FIV), a deadly condition that attacks infection-fighting T-cells as AIDS does.

The researchers including Mayo Clinic molecular biologist Eric Poeschla inserted genes into feline eggs before sperm fertilization. They added a gene for a rhesus macaque protein, known as a "restriction factor," that can prevent infection by FIV, and a jellyfish gene for tracking the cells that also makes the kitties glow a spooky green.

When cells were taken from the cats and exposed to FIV, they were found to be resistant; the animals themselves will also be exposed to the virus in the future. … Read more

With some 26 million Americans living with diabetes (8.3 percent of the U.S. population), according to the American Diabetes Association, a lot of research is going into how to make blood glucose monitoring more effective and affordable.

Researchers at Arizona State University and the Mayo Clinic are partnering up to develop a monitor that enables people to dab their tear ducts instead of prick their fingers--which could be a big deal for those who currently draw blood as many as a dozen times a day to monitor their blood glucose levels.

"The problem with current self-monitoring blood glucose technologies is not so much the sensor, it's the painful finger prick," Jeffrey LaBelle, a bioengineer and chief designer, said in a news release. "This new technology might encourage patients to check their blood sugars more often, which could lead to better control of their diabetes by a simple touch to the eye."

The team reported on the first stage of their research on the sensor in Diabetes Science and Technology in March 2010, and quickly sparked interest from Arizona-based nonprofit BioAccel, which works to speed up the process of bringing biomedical technologies to the marketplace.

Using funding from BioAccel, the team is now compiling data to apply for human clinical trials of the device, but major challenges remain, including accuracy, efficiency, speed of performing the test, reproducible results, and of course making sure the test sample does not evaporate before it can be read.… Read more

Intel is using its technology know-how to pave the way for safer football helmets with the goal of reducing serious injuries on the field.

Working with football equipment designer Riddell and a host of universities, the chipmaker is tapping into its own supercomputers and workstations to simulate the effects of a football collision on the brain. Data from those simulations will then be used to help design safer football helmets.

Intel recently demoed the simulation at the SC10 conference in New Orleans. Simulated collisions on the football field are processed by groups of Intel Xeon-based workstations linked together. Using real-time … Read more

PsychReport is a clinical case management tool for professionals in the field of psychology. Although the program seems to have a lot of useful features, it's ultimately undermined by its clunky interface.

We were turned off by the program almost immediately when we opened it and the creepy Microsoft Sam text-to-speech voice announced "PsychReport." From there, it only got worse; the program announces the name of each module as it's opened, and there doesn't seem to be any way to turn this annoying and pointless feature off. The main menu is a mix of icons … Read more

For centuries, humans have looked for signs of diseased tissue and organs by tapping the outside of the body to measure stiffness. Obviously such a method is only so effective, especially when trying to evaluate someone's liver, say, or heart. And more modern biopsies, while highly effective, are invasive procedures that involve removing tissue for examination.

Since 2007, researchers at the Mayo Clinic in Rochester, Minn., have been working with magnetic resonance elastography (MRE), a medical imaging technique developed to non-invasively diagnose and monitor disease.

The device they use, MR-Touch, uses low-frequency sound waves for just 15 seconds at … Read more

The Mayo Clinic on Tuesday said it will build a personal health record service based on Microsoft's HealthVault technology.

The product, Mayo Clinic Health Manager, will initially focus on general pediatric and adult health issues, immunization records, pregnancy, and asthma. In the coming months, the clinic will add tools to help manage chronic conditions, such as Type 2 diabetes, high cholesterol, and high blood pressure.

"Mayo Clinic Health Manager can help patients share information more easily with their doctors and manage their own health better between office visits," said Mayo Clinic doctor Sidna Tulledge-Scheitel, who also serves … Read more

I mentioned the other day that I've been hearing about scads of new open-source projects, commercial and otherwise, but I had not yet heard of OpenClinica, which TMCnet profiles today.

Since its debut in 2005, OpenClinica [developed by Akaza Research] has quickly become the most popular open source clinical trials software in the world. Akaza Research previously announced that it had experienced 2,000 OpenClinica downloads as of August 2006. Today's announcement represents a growth of 700 percent since that time....Akaza Research takes the position that its professional open source approach is key to helping to facilitate … Read more

People ascribe great healing powers to LED lamps and are willing to make some notable sacrifices to use them. But the Med Spa Clinic in England has taken the concept to its therapeutic extreme.

The "Oxy-LED Light Spa Capsule" isn't directed only at the face as are other products, instead spreading its magic wavelengths over the entire body. The reason: Not only is it an emotional enhancer, but the pricey full-body spa supposedly promotes weight loss when combined with other therapies by causing "intense physical stimulation," according to BornRich. With claims like that, it might … Read more

Update at 12:19 PM PT: This story was updated to reflect the World Privacy Forum's position on PHRs in general.

Google is set to announce on Thursday that it will be using the Cleveland Clinic hospital in Cleveland, Ohio as the pilot site for its new personal health records initiative.

Between 1,500 and 10,000 patients at the Cleveland, Ohio, facility will participate in the project's test run, volunteering to have their medical records transferred to their Google accounts. The hospital already keeps electronic records for over 100,000 patients in an internal system called MyChart, … Read more