Cocaine

What would you do if you found a bag of white powder tucked neatly into the textbook you just bought on the Amazon Marketplace?

If you're smart, you'd take it to the police like Sophia Stockton, a junior at a university in Kansas who discovered something similar in the pages of a history book called "Understanding Terrorism: Challenges, Perspectives and Issues."

While we're on the topic of narcotics, don't forget to tune into President Obama's Q+A on Google+ Hangout tonight at 5:30 p.m. ET, live from the West Wing of … Read more

A U.K. company is now unveiling what it calls the world's first prototype handheld device that doubles as a fingerprint scanner and drug testing device.

In a matter of minutes, the portable device can detect the presence of a wide range of drugs using dyed antibodies that, as we reported back in July, stick to metabolites in the sweat of the fingerprints and change color depending on the presence of drugs.

"The launch of this prototype is a significant milestone," Paul Yaltes of development firm Intelligent Fingerprinting said in a statement. "There has already been … Read more

The notion of erasing memories associated with painful or harmful pasts is not a new one. But it has remained just that: a notion.

Now scientists in Israel say they have devised a method to erase memories that trigger cravings in rats addicted to cocaine--a method that works so well it actually results in rats ignoring the place where they had been scoring the drug.

"Memories can trigger a desire for the drug, including memories of the drug itself, the needle, or the environment in which the drug was consumed," says Hebrew University researcher Rami Yaka. "This research indicates the possibility of erasing these memories in a way that will allow addicts to cancel the associations they have in their minds regarding the drug."

The team worked with a small protein called ZIP, which has been found in other studies in recent years to erase memories and even, as a result, inhibit learning processes.

After giving the rats cocaine in a designated spot in their pens for a few weeks, the team injected ZIP into the nucleus accumbens, a brain region known to control pleasure, reward, fear, and more, and then returned the rats to their pens. The rats proceeded to ignore the location they had only recently sought out, suggesting they no longer remembered either the place, the effect of the drug, or perhaps both.

Yaka, who will present his team's findings at the Facing Tomorrow 2011 conference in Jerusalem next week, sees possibilities not just for drug addicts but also those suffering from posttraumatic stress disorder and other psychological conditions.

Of course, it remains unclear whether the protein erases selective memories associated with drugs, or if other pleasure-and-reward memories are also affected. Will one also forget the sweetness of chocolate? The ecstasies of copulation? The kiss of a gentle summer's breeze?

If so, will it be worth it?… Read more

It is not easy being Paris Hilton. You have to spend so much of your time focused on the "being Paris Hilton" part that it leaves very little time for much else. Like considering the state of the nation. Or remembering what pictures you tweeted a month ago.

My fingers flicker with sympathy because Hilton seems to have got herself into a slight pickle. A slight pickle that might be less slight than her much-loved sex video.

An SUV in which she was accompanied by her boyfriend was stopped Friday in Las Vegas when police reportedly detected the … Read more

Cocaine addiction is notoriously tough to beat. Engineers at the University of Missouri in Columbia, using computational models, think they now better understand why.

"Our model showed that the glutamate transporters, a protein present around these connections that remove glutamate, are almost 40 percent less functional after chronic cocaine usage," says Ashwin Mohan, a doctoral student in the department of electrical and computer engineering. "This damage is long lasting, and there is no way for the brain to regulate itself. Thus, the brain structure in this context actually changes in cocaine addicts."

The team found that … Read more

It is said by those who know (and those who merely have a sniff of the facts) that cocaine is quite a popular entertainment for many a technical mind.

I am told that it provides a temporary feeling of invincibility, one that can be useful when networking, selling a less than watertight notion or attempting to persuade a member of your target sex that you are, indeed, a person worth sharing combining notions with.

Now the Central Institute of Mental Health in Mannheim, Germany has found good reason for coke users to toss aside their guilt and let their parents … Read more

Libe Goad joins the guys of the 404 to talk about how the Wii gets hacked, GTA IV gets a lot of cash, get in shape with Wii Fit, Boom some Blox and some silly-ass stop signs. We also make fun of her husband, but shh...don't tell him.

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