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Medical tools

New virus-detecting lab on a chip gets even better

A team of engineers and chemists at Brigham Young University has created a silicon microchip they say can reliably detect specific proteins or viruses from even small samples at low concentrations.

Their invention, which is forthcoming in the paper version of the journal Lab on a Chip, works much the way a coin sorter does, only on a microscopic scale, screening for particles purely by size. This renders sample sizes and concentration levels almost irrelevant, because particles are trapped by size, not number, thereby allowing for much earlier detections of viruses.

"Most of the tests that you're given … Read more

Magnetic nanoparticles target human cancer cells

In 2008, scientists at the Georgia Institute of Technology and the Ovarian Cancer Institute developed a potential treatment to fight cancer using magnetic nanoparticles designed to attach themselves to cancer cells. They found in their groundbreaking tests on mice that the particles not only attached to cancer cells, but they also moved those cells.

In what may well prove to be some of the most exciting health news in the year to come, the group announced in the journal Nanomedicine in December and further publicized on Tuesday that it has replicated the study on human cancer cells, with the nanoparticles … Read more

Breakthrough heart scan leads to early diagnosis

Magnetometers are typically associated with large-scale projects such as digging for oil, locating submerged objects, and detecting archaeological sites from spacecraft. But now, with unprecedented sensitivity to magnetic fluctuations, a prototype being developed at the University of Leeds could greatly improve the diagnosis of cardiac conditions.

"The new system gets round previous difficulties by putting the actual detector in its own magnetic shield," says University of Leeds Professor Ben Varcoe, who is leading the research team.

Using a magnetometer to examine the cardiovascular health of humans has, up until now, been expensive and complicated, and has required containing … Read more

A migraine treatment for needle-phobes

If you have the poor fortune of suffering from both migraines and needle phobia, I have good news and bad news.

The good news is that five months after receiving FDA approval, the Sumavel DosePro sumatriptan delivery system--due to hit the shelves this month--manages to be both subcutaneous and needle-free, and can bring relief from migraines in as few as 10 minutes without having to push in any needles.

The bad news is that the drug delivery system may be more painful than using a good old-fashioned needle. In order to deliver the migraine pain reliever sumatriptan through the skin without the aid of a small, quick, sharp needle, this delivery system uses a high burst of nitrogen to shoot the drug through the skin. Umm, ouch?

One reviewer of the delivery system says people are reporting that the system is painful and can result in bruising, swelling, bleeding, and the like. If your fear of needles is extreme, this lack of a needle may be worth the fuss. But if your fear is mild, this may not be the approach for you.… Read more

Got diabetes? No more pricks, just breathe on this

Our breath can say a lot about us--and not just what we had for lunch.

Engineers at the University of Florida are reporting that they have designed a tiny and affordable sensor that can do what has up until now been considered impossible: detect glucose (as well as pH and alkalinity) levels in breath condensate.

Fan Ren, professor of chemical engineering and a researcher for this project, says that the team's most recent research, published in the January issue of IEEE Sensors Journal, upsets long-held assumptions that glucose levels in breath are too small for accurate readings; the sensor, … Read more

Diagnosing PTSD using brain imaging

Post-traumatic stress, which is estimated to afflict one in five veterans of the Iraq and Afghanistan wars alone, is typically diagnosed through behavioral screenings and is often considered a "soft" disorder with no known biomarkers.

"It's like depression in that it can be hidden by the sufferer, it can be latent, and it can be re-activated," says Apostolos Georgopoulos, a professor of neuroscience at the University of Minnesota. "That's a major issue for the Army, which has to decide whether to re-deploy troops who have had it."

Georgopoulos has previously discovered biomarkers … Read more

Video Scout: For surgeons or James Bond?

We've come a long way, baby.

Back when the first endoscope was developed in 1806 to probe "the canals and cavities of the human body," the Vienna Medical Society ruled it to be something of an inappropriate technology, and improvements on such devices were slow-going for decades.

Today the field of endoscopy has splintered out into dozens of areas, playing key roles in procedures that involve almost every part of the human body, from colonoscopies (colon) to rhinoscopies (nose), colposcopies (cervix) to bronchoscopies (airways). The tiny cameras used in these procedures make David Pogue's column look like a review of ancient relics.

At just 3 millimeters in diameter, BC Tech's Video Scout is one of the smallest medical cameras in the world, according to the company's VP of business development, Charlie Skinner:

Medical companies can integrate the Video Scout into biopsy tools, ablation wands, catheters, tissue cutters, scopes and more. We're confident this sort of low cost imaging technology will usher in a new wave of disposable medical products with built in video cameras.

The high cost of health care has led to a big push for more affordable surgical devices. Video Scout has great potential to be a low-cost, single-use alternative to more expensive industry standards. CEO Ben Clawson takes the upside even further:… Read more

Can we diagnose and destroy cancer in one sitting?

Let's say you find a lump somewhere and decide to go in for an exam. And let's say there was a little box to check that allows you to get a shot that targets and kills cancerous cells right then and there, no surgery, no waiting, and possibly no radiation or chemo therapy down the road. Would you check the box?

Since time matters when it comes to cancer, the creation of a single nanoparticle--traceable in real time via MRI--that tags and zaps cancer cells all in one procedure has a team of researchers raising their eyebrows in … Read more

Microsoft to buy Sentillion for health care software

Microsoft is adding another player to its portfolio of health care offerings.

The software powerhouse said Thursday that it plans to buy Sentillion, a privately held company that supplies software to health care professionals. Microsoft hopes to combine Sentillion's technologies with its own Amalga Unified Intelligence System (UIS). The goal is to offer integrated technology that can help health care providers more easily access patient data from across multiple sources.

As doctors and hospitals ramp up to make better use of e-health technology, they face a confusing array of tools and systems that could make their jobs more difficult. … Read more

Disease-detecting device vibrates with potential

For centuries, humans have looked for signs of diseased tissue and organs by tapping the outside of the body to measure stiffness. Obviously such a method is only so effective, especially when trying to evaluate someone's liver, say, or heart. And more modern biopsies, while highly effective, are invasive procedures that involve removing tissue for examination.

Since 2007, researchers at the Mayo Clinic in Rochester, Minn., have been working with magnetic resonance elastography (MRE), a medical imaging technique developed to non-invasively diagnose and monitor disease.

The device they use, MR-Touch, uses low-frequency sound waves for just 15 seconds at … Read more